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Coadministration of pexidartinib (a CYP3A4 inducer) with sensitive CYP3A substrates may perhaps result in serious therapeutic failures. If concomitant use is unavoidable, boost the CYP3A substrate dosage in accordance with authorised item labeling.Coadministration with CYP3A4 substrates, significantly All those with a slim therapeutic index, may re